NIH Parent R21 & R03 (exploratory / small grants)
National Institutes of Health
R21 funds high-risk exploratory projects β $275K direct costs total over two years, with a maximum of $200K in any one year. R03 funds small discrete projects. NHLBI, NINDS, NIAMS, NICHD, and NCATS participate in the parent R21; NIGMS does not. R03 participation varies by institute and is listed on individual IC pages.
Suits new BTHS models, biomarker pilots, and mechanism-testing studies β the work that cannot yet show the preliminary data an R01 expects.
Same broad eligibility as the R01; foreign organizations eligible for the R21.
Via eRA Commons / Grants.gov / ASSIST under the current parent announcements; standard due dates Feb 16, Jun 16, Oct 16.
/grants/nih-parent-r21-and-r03-exploratory-small-grants/
Last updated August 28, 2026 Β· Suggest an update to this entry