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NIH Parent R21 & R03 (exploratory / small grants)

National Institutes of Health

Award
R21: $275K direct/2 yrs; R03: ~$50K/yr, 2 yrs
Deadline
Feb 16, Jun 16, Oct 16
Award type
Cash grant
Focus
Basic science Β· Preclinical & therapeutics

R21 funds high-risk exploratory projects β€” $275K direct costs total over two years, with a maximum of $200K in any one year. R03 funds small discrete projects. NHLBI, NINDS, NIAMS, NICHD, and NCATS participate in the parent R21; NIGMS does not. R03 participation varies by institute and is listed on individual IC pages.

Why it's in this index

Suits new BTHS models, biomarker pilots, and mechanism-testing studies β€” the work that cannot yet show the preliminary data an R01 expects.

Who can apply

Same broad eligibility as the R01; foreign organizations eligible for the R21.

How to apply

Via eRA Commons / Grants.gov / ASSIST under the current parent announcements; standard due dates Feb 16, Jun 16, Oct 16.

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Last updated August 28, 2026 Β· Suggest an update to this entry